But to my mind that misses the point. However, that’s a pretty technical paper. These are actually the same, other than a constant term in the front, a combinatoric term for the binomial does not depend on theta. Lee, Michael D, and Eric-Jan Wagenmakers. In the rainy day problem, you are told that I really am carrying an umbrella. Again, let’s not worry about the maths, and instead think about our intuitions. – Sir Ronald Fisher (1925). But until that day arrives, I stand by my claim that default Bayes factor methods are much more robust in the face of data analysis practices as they exist in the real world. That’s why the output of these functions tells you what the margin for error is.↩, Apparently this omission is deliberate. supports HTML5 video. \begin{array}{ccccc}\displaystyle http://CRAN.R-project.org/package=BayesFactor. In fact, it can do a few other neat things that I haven’t covered in the book at all. Okay, some quick reading through the help files hints that support for larger contingency tables is coming, but it’s not been implemented yet. Bayes’ rule cannot stop people from lying, nor can it stop them from rigging an experiment. What does the Bayesian version of the \(t\)-test look like? My preference is usually to go for something a little briefer. \mbox{Posterior odds} && \mbox{Bayes factor} && \mbox{Prior odds} A good system for statistical inference should still work even when it is used by actual humans. Now, because this table is so useful, I want to make sure you understand what all the elements correspond to, and how they written: Finally, let’s use “proper” statistical notation. In his opinion, if we take \(p<.05\) to mean there is “a real effect”, then “we shall not often be astray”. In this case, the alternative is that there is a relationship between species and choice: that is, they are not independent. The result is significant with a sample size of \(N=50\), so wouldn’t it be wasteful and inefficient to keep collecting data? So, what might you believe about whether it will rain today? \frac{P(h_1 | d)}{P(h_0 | d)} = \frac{0.75}{0.25} = 3 \end{array} Morey and Rouder (2015) built their Bayesian tests of association using the paper by Gunel and Dickey (1974), the specific test we used assumes that the experiment relied on a joint multinomial sampling plan, and indeed the Bayes factor of 15.92 is moderately strong evidence. So, what’s the chance that you’ll make it to the end of the experiment and (correctly) conclude that there is no effect? The command that we need is. Again, I find it useful to frame things the other way around, so I’d refer to this as evidence of about 3 to 1 in favour of an effect of therapy. The question that you have to answer for yourself is this: how do you want to do your statistics? To me, this is the big promise of the Bayesian approach: you do the analysis you really want to do, and express what you really believe the data are telling you. After all, the whole point of the \(p<.05\) criterion is to control the Type I error rate at 5%, so what we’d hope is that there’s only a 5% chance of falsely rejecting the null hypothesis in this situation. How do we run an equivalent test as a Bayesian? This is because the BayesFactor package often has to run some simulations to compute approximate Bayes factors. Time to change gears. As it turns out, the truth of the matter is that there is no real effect to be found: the null hypothesis is true. Ultimately it depends on what you think is right. P(h_0 | d) = \frac{P(d|h_0) P(h_0)}{P(d)} In other words, what we want is the Bayes factor corresponding to this comparison: As it happens, we can read the answer to this straight off the table because it corresponds to a comparison between the model in line 2 of the table and the model in line 3: the Bayes factor in this case represents evidence for the null of 0.001 to 1. In any case, note that all the numbers listed above make sense if the Bayes factor is greater than 1 (i.e., the evidence favours the alternative hypothesis). However, there’s no guarantee that will be true. The important thing for our purposes is the fact that dan.sleep is significant at \(p<.001\) and neither of the other variables are. 1 Bayesian Inference for the Normal Distribution 1. . So the probability that both of these things are true is calculated by multiplying the two: \[ In other words, before being told anything about what actually happened, you think that there is a 4.5% probability that today will be a rainy day and that I will remember an umbrella. The reason why these four tools appear in most introductory statistics texts is that these are the bread and butter tools of science. \frac{P(h_1 | d)}{P(h_0 | d)} &=& \displaystyle\frac{P(d|h_1)}{P(d|h_0)} &\times& \displaystyle\frac{P(h_1)}{P(h_0)} \\[6pt] \\[-2pt] Again, adding the vertical line helps us see the maximum at 0.18. For instance, if we want to identify the best model we could use the same commands that we used in the last section. In this problem, I have presented you with a single piece of data (\(d =\) I’m carrying the umbrella), and I’m asking you to tell me your beliefs about whether it’s raining. Notice that I don’t bother including the version number? In the line above, the text Null, mu1-mu2 = 0 is just telling you that the null hypothesis is that there are no differences between means. At the bottom we have some techical rubbish, and at the top we have some information about the Bayes factors. What’s wrong with that? However, notice that there’s no analog of the var.equal argument. In real life, this is exactly what every researcher does. Back in Chapter@refch:ttest I suggested you could analyse this kind of data using the independentSamplesTTest() function in the lsr package. At some stage I might consider adding a function to the lsr package that would automate this process and construct something like a “Bayesian Type II ANOVA table” from the output of the anovaBF() function. But that’s a recipe for career suicide. So the only thing left in the output is the bit that reads. Ultimately, isn’t that what you want your statistical tests to tell you? In any case here is a brief example. The cake is a lie. If it ever reaches the point where sequential methods become the norm among experimental psychologists and I’m no longer forced to read 20 extremely dubious ANOVAs a day, I promise I’ll rewrite this section and dial down the vitriol. No matter how unlikely you thought it was, you must now adjust your beliefs to accommodate the fact that you now know that I have an umbrella.258 To reflect this new knowledge, our revised table must have the following numbers: In other words, the facts have eliminated any possibility of “no umbrella”, so we have to put zeros into any cell in the table that implies that I’m not carrying an umbrella. You can work this out by simple arithmetic (i.e., \(0.06 / 1 \approx 16\)), but the other way to do it is to directly compare the models. The first half of this chapter was focused primarily on the theoretical underpinnings of Bayesian statistics. Today I am going to implement a Bayesian linear regression in R from scratch. For the Poisson sampling plan (i.e., nothing fixed), the command you need is identical except for the sampleType argument: Notice that the Bayes factor of 28:1 here is not the identical to the Bayes factor of 16:1 that we obtained from the last test. Be honest with yourself. It’s not an easy thing to do because a \(p\)-value is a fundamentally different kind of calculation to a Bayes factor, and they don’t measure the same thing. So the relevant comparison is between lines 2 and 1 in the table. You are not allowed to use the data to decide when to terminate the experiment. First, the concept of “statistical significance” is pretty closely tied with \(p\)-values, so it reads slightly strangely. \]. If you can remember back that far, you’ll recall that there are several versions of the \(t\)-test. I now want to briefly describe how to do Bayesian versions of various statistical tests. How to do Bayesian inference with some sample data, and how to estimate parameters for your own data. It’s not that Bayesian methods are foolproof. But, just like last time, there’s not a lot of information here that you actually need to process. However, there have been some attempts to work out the relationship between the two, and it’s somewhat surprising. To an ideological frequentist, this sentence should be meaningless. What that means is that the Bayes factors are now comparing each of those 3 models listed against the dan.grump ~ dan.sleep model. Or if we look at line 1, we can see that the odds are about \(1.6 \times 10^{34}\) that a model containing the dan.sleep variable (but no others) is better than the intercept only model. Bayes Bayes Bayes Bayes Bayes. None of these tools include a correction to deal with “data peeking”: they all assume that you’re not doing it. Every single time an observation arrives, run a Bayesian \(t\)-test (Section 17.7 and look at the Bayes factor. However, for the sake of everyone’s sanity, throughout this chapter I’ve decided to rely on one R package to do the work. None of us are without sin. There is a book available in the “Use R!” series on using R for multivariate analyses, Bayesian Computation with R by Jim Albert. I spelled out “Bayes factor” rather than truncating it to “BF” because not everyone knows the abbreviation. The resulting Bayes factor of 15.92 to 1 in favour of the alternative hypothesis indicates that there is moderately strong evidence for the non-independence of species and choice. All of them. The first kind of statistical inference problem I discussed in this book appeared in Chapter 12, in which we discussed categorical data analysis problems. You can specify the sampling plan using the sampleType argument. Bayesian approach, in contrast, provides true probabilities to quantify the uncertainty about a certain hypothesis, but requires the use of a first belief about how likely this hypothesis is true, known as prior, to be able to derive the. Rich Morey and colleagues had the idea first. That’s not surprising, of course: that’s our prior. Finally, the evidence against an interaction is very weak, at 1.01:1. \mbox{BF} = \frac{P(d|h_1)}{P(d|h_0)} = \frac{0.1}{0.2} = 0.5 In Chapter 11 I described the orthodox approach to hypothesis testing. Using the equations given above, Bayes factor here would be: \[ It took an entire chapter to describe, because null hypothesis testing is a very elaborate contraption that people find very hard to make sense of. Okay, let’s think about option number 2. Once you’ve made the jump, you no longer have to wrap your head around counterinuitive definitions of \(p\)-values. A theory for statistical inference has to acknowledge this. The BFindepSample part just tells you that you ran an independent samples \(t\)-test, and the JZS part is technical information that is a little beyond the scope of this book.272 Clearly, there’s nothing to worry about in that part. As I mentioned earlier, this corresponds to the “independent multinomial” sampling plan. And in fact you’re right: the city of Adelaide where I live has a Mediterranean climate, very similar to southern California, southern Europe or northern Africa. We could probably reject the null with some confidence! You don’t have conclusive results, so you decide to collect some more data and re-run the analysis. So I’m not actually introducing any “new” rules here, I’m just using the same rule in a different way.↩, Obviously, this is a highly simplified story. You can type ?ttestBF to get more details.↩, Again, guys, sorry if I’ve misread you.↩, I don’t even disagree with them: it’s not at all obvious why a Bayesian ANOVA should reproduce (say) the same set of model comparisons that the Type II testing strategy uses. To my mind, this write up is unclear. In this example, I’m going to pretend that you decided that dan.grump ~ dan.sleep + baby.sleep is the model you think is best. However, sequential analysis methods are constructed in a very different fashion to the “standard” version of null hypothesis testing. In Chapter 16 I recommended using the Anova() function from the car package to produce the ANOVA table, because it uses Type II tests by default. This “conditional probability” is written \(P(d|h)\), which you can read as “the probability of \(d\) given \(h\)”. What two numbers should we put in the empty cells? So, what is the probability that today is a rainy day and I remember to carry an umbrella? Here’s how you do that. If I were to follow the same progression that I used when developing the orthodox tests you’d expect to see ANOVA next, but I think it’s a little clearer if we start with regression. Adding that in makes it very clearly that this likelihood is maximized at 72 over 400. Before moving on, it’s worth highlighting the difference between the orthodox test results and the Bayesian one. All significance tests have been based on the 95 percent level of confidence. In this case, all we needed to do is return a computed value. I also know that you can explictly design studies with interim analyses in mind. Let’s suppose that on rainy days I remember my umbrella about 30% of the time (I really am awful at this). Well, consider the following scenario. Of the two, I tend to prefer the Kass and Raftery (1995) table because it’s a bit more conservative. That seems silly. The development of the programming language Stan has made doing Bayesian analysis easier for social sciences. For example, suppose that the likelihood of the data under the null hypothesis \(P(d|h_0)\) is equal to 0.2, and the corresponding likelihood \(P(d|h_0)\) under the alternative hypothesis is 0.1. Even in the classical version of ANOVA there are several different “things” that ANOVA might correspond to. There are two hypotheses that we want to compare, a null hypothesis \(h_0\) and an alternative hypothesis \(h_1\). All the \(p\)-values you calculated in the past and all the \(p\)-values you will calculate in the future. In my experience that’s a pretty typical outcome. If you’re the kind of person who would choose to “collect more data” in real life, it implies that you are not making decisions in accordance with the rules of null hypothesis testing. You aren’t even allowed to change your data analyis strategy after looking at data. However, I have to stop somewhere, and so there’s only one other topic I want to cover: Bayesian ANOVA. I hate to bring this up, but some statisticians would object to me using the word “likelihood” here. As we discussed earlier, the prior tells us that the probability of a rainy day is 15%, and the likelihood tells us that the probability of me remembering my umbrella on a rainy day is 30%. The help documentation to the contingencyTableBF() gives this explanation: “the argument priorConcentration indexes the expected deviation from the null hypothesis under the alternative, and corresponds to Gunel and Dickey’s (1974) \(a\) parameter.” As I write this I’m about halfway through the Gunel and Dickey paper, and I agree that setting \(a=1\) is a pretty sensible default choice, since it corresponds to an assumption that you have very little a priori knowledge about the contingency table.↩, In some of the later examples, you’ll see that this number is not always 0%. is known. In the Bayesian paradigm, all statistical inference flows from this one simple rule. What’s the Bayesian analog of this? & = & 0.30 \times 0.15 \\ Plotting this as a series of points doesn't give us necessarily the best picture. If anyone has ever been entitled to express an opinion about the intended function of \(p\)-values, it’s Fisher. The important thing isn’t the number itself: rather, the important thing is that it gives us some confidence that our calculations are sensible! The likelihood is a function of the mortality rate theta. The cake is a lie. (a=1) : 8.294321 @plusorminus0%, #Bayes factor type: BFcontingencyTable, hypergeometric, "`mood.gain ~ drug + therapy + drug:therapy`", Learning statistics with R: A tutorial for psychology students and other beginners. 2015. In this passage, taken from his classic guide Statistical Methods for Research Workers, he’s pretty clear about what it means to reject a null hypothesis at \(p<.05\). They’ll argue it’s borderline significant. On the right hand side, we have the prior odds, which indicates what you thought before seeing the data. This is a guide on how to conduct Meta-Analyses in R. Chapter 13 Bayesian Meta-Analysis After delving into rather advanced extensions of Meta-Analysis, such as Network Meta-Analysis and Multilevel Meta-Analysis, let us now take one step back and look at “conventional” meta-analytical models again, but this time from another angle. So what regressionBF() does is treat the intercept only model as the null hypothesis, and print out the Bayes factors for all other models when compared against that null. Even if you’re a more pragmatic frequentist, it’s still the wrong definition of a \(p\)-value. Honestly, there’s nothing wrong with it. The fact remains that, quite contrary to Fisher’s claim, if you reject at \(p<.05\) you shall quite often go astray. If the \(t\)-tests says \(p<.05\) then you stop the experiment and report a significant result. Fortunately, no-one will notice. BN • Graphical Bayesian “Belief” Network (BBN) • Prior, Likelihood and Posterior Python • BN ecosystem in Python R • BN ecosystem in R PyDataDC 10/8/2016BAYESIAN NETWORK MODELING USING PYTHON AND R 20 And because it assumes the experiment is over, it only considers two possible decisions. At the other end of the spectrum is the full model in which all three variables matter. Which again is a function of n, y and theta. We will compare the Bayesian approach to the more commonly-taught Frequentist approach, and see some of the benefits of the Bayesian approach. I didn’t bother indicating whether this was “moderate” evidence or “strong” evidence, because the odds themselves tell you! Here we go from 0.01, 2.99, in increments of 0.01. In the rainy day problem, the data corresponds to the observation that I do or do not have an umbrella. P(\mbox{rainy}, \mbox{umbrella}) & = & P(\mbox{umbrella} | \mbox{rainy}) \times P(\mbox{rainy}) \\ The relevant null hypothesis is the one that contains only therapy, and the Bayes factor in question is 954:1. \uparrow && \uparrow && \uparrow \\[6pt] The data that you need to give to this function is the contingency table itself (i.e., the crosstab variable above), so you might be expecting to use a command like this: However, if you try this you’ll get an error message. I’ve rounded 15.92 to 16, because there’s not really any important difference between 15.92:1 and 16:1. – Inigo Montoya, The Princess Bride261. Not just the \(p\)-values that you calculated for this study. In this data set, we supposedly sampled 180 beings and measured two things. If the data are consistent with a hypothesis, my belief in that hypothesis is strengthened. \], It’s all so simple that I feel like an idiot even bothering to write these equations down, since all I’m doing is copying Bayes rule from the previous section.260. And yes, these rules are surprisingly strict. At the bottom, the output defines the null hypothesis for you: in this case, the null hypothesis is that there is no relationship between species and choice. For instance, the model that contains the interaction term is almost as good as the model without the interaction, since the Bayes factor is 0.98. BioGeoBEARS: BioGeography with Bayesian (and Likelihood) Evolutionary Analysis in R Scripts BioGeoBEARS allows probabilistic inference of both historical biogeography (ancestral geographic ranges on a phylogeny) as well as comparison of different models of range evolution. – Ambrosius Macrobius267, Good rules for statistical testing have to acknowledge human frailty. Johnson, Valen E. 2013. “Revised Standards for Statistical Evidence.” Proceedings of the National Academy of Sciences, no. Some reviewers will think that \(p=.072\) is not really a null result. It turns out that the Type I error rate is much much lower than the 49% rate that we were getting by using the orthodox \(t\)-test. As usual we have a formula argument in which we specify the outcome variable on the left hand side and the grouping variable on the right. Classes which have methods for thisfunction include: "glm", "lm", "nls" and"Arima". In any case, by convention we like to pretend that we give equal consideration to both the null hypothesis and the alternative, in which case the prior odds equals 1, and the posterior odds becomes the same as the Bayes factor. I absolutely know that if you adopt a sequential analysis perspective you can avoid these errors within the orthodox framework. That being said, I can talk a little about why I prefer the Bayesian approach. Because frequentist methods are ubiquitous in scientific papers, every student of statistics needs to understand those methods, otherwise they will be unable to make sense of what those papers are saying! I should note in passing that I’m not the first person to use this quote to complain about frequentist methods. Look, I’m not dumb. Before reading any further, I urge you to take some time to think about it. As I mentioned earlier, there’s still no convention on how to do that, but I usually go for something like this: A Bayesian Type II ANOVA found evidence for main effects of drug (Bayes factor: 954:1) and therapy (Bayes factor: 3:1), but no clear evidence for or against an interaction (Bayes factor: 1:1). I’m not alone in doing this. Let’s suppose that the null hypothesis is true about half the time (i.e., the prior probability of \(H_0\) is 0.5), and we use those numbers to work out the posterior probability of the null hypothesis given that it has been rejected at \(p<.05\). If it is 3:1 or more in favour of the alternative, stop the experiment and reject the null. So what we expect to see in our final table is some numbers that preserve the fact that “rain and umbrella” is slightly more plausible than “dry and umbrella”, while still ensuring that numbers in the table add up. When the study starts out you follow the rules, refusing to look at the data or run any tests. How do we do the same thing using Bayesian methods? The BayesFactor package contains a function called ttestBF() that is flexible enough to run several different versions of the \(t\)-test. At the end of this section I’ll give a precise description of how Bayesian reasoning works, but first I want to work through a simple example in order to introduce the key ideas. To me, it makes a lot more sense to turn the equation “upside down”, and report the amount op evidence in favour of the null. \]. So the command is: So that’s pretty straightforward: it’s exactly what we’ve been doing throughout the book. Let's plot the likelihood function for this example. \]. If you’re interested in learning more about the Bayesian approach, there are many good books you could look into. R has many modeling packages devoted to Bayesian analysis such that there is a Task View specific to the topic. Remember what I said back in Section 16.6: under the hood, ANOVA is no different to regression, and both are just different examples of a linear model. I don’t know about you, but in my opinion an evidentiary standard that ensures you’ll be wrong on 20% of your decisions isn’t good enough. And as a consequence you’ve transformed the decision-making procedure into one that looks more like this: The “basic” theory of null hypothesis testing isn’t built to handle this sort of thing, not in the form I described back in Chapter 11. We worked out that the joint probability of “rain and umbrella” was 4.5%, and the joint probability of “dry and umbrella” was 4.25%. You probably know that I live in Australia, and that much of Australia is hot and dry. Yet, as it turns out, when faced with a “trigger happy” researcher who keeps running hypothesis tests as the data come in, the Bayesian approach is much more effective. If it were up to me, I’d have called the “positive evidence” category “weak evidence”. What’s next? It’s now time to consider what happens to our beliefs when we are actually given the data. However, there are of course four possible things that could happen, right? What this table is telling you is that, after being told that I’m carrying an umbrella, you believe that there’s a 51.4% chance that today will be a rainy day, and a 48.6% chance that it won’t. Well, like every other bloody thing in statistics, there’s a lot of different ways you could do it. This might be a little bit difficult to see in the plot. Well, keep in mind that if you do, your Type I error rate at \(p<.05\) just ballooned out to 8%. I’m not going to talk about those complexities in this book, but I do want to highlight that although this simple story is true as far as it goes, real life is messier than I’m able to cover in an introductory stats textbook.↩, http://www.imdb.com/title/tt0093779/quotes. Also, you know for a fact that I am carrying an umbrella, so the column sum on the left must be 1 to correctly describe the fact that \(P(\mbox{umbrella})=1\). The best model is drug + therapy, so all the other models are being compared to that. You’ve found the regression model with the highest Bayes factor (i.e., dan.grump ~ dan.sleep), and you know that the evidence for that model over the next best alternative (i.e., dan.grump ~ dan.sleep + day) is about 16:1. However, there have been some attempts to quantify the standards of evidence that would be considered meaningful in a scientific context. That gives us this table: This is a very useful table, so it’s worth taking a moment to think about what all these numbers are telling us. Besides, if you keep writing the word “Bayes” over and over again it starts to look stupid. We shall not often be astray if we draw a conventional line at .05 and consider that [smaller values of \(p\)] indicate a real discrepancy. If a researcher is determined to cheat, they can always do so. You might be thinking that this is all pretty laborious, and I’ll concede that’s true. If I’d chosen a 5:1 Bayes factor instead, the results would look even better for the Bayesian approach.↩, http://www.quotationspage.com/quotes/Ambrosius_Macrobius/↩, Okay, I just know that some knowledgeable frequentists will read this and start complaining about this section. 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The log likelihood, say log like you thought before seeing the data were were up to this point I. Consequences of “just one peek” can be we tend to prefer the and... Did so in order to appreciate the course be written to handlespecific classes objects! Is whether there’s any difference in the range 3:1 to 20:1 is “weak” or evidence...

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