Display Name: Sebacic acid EC Number: 203-845-5 EC Name: Sebacic acid CAS Number: 111-20-6 Molecular formula: C10H18O4 IUPAC Name: decanedioic acid All formulas are in Hill order. Its name comes from the Greek word στέαρ "stéar", which means tallow. 250°C, so that saponification, leading to the formation of ricinoleic acid; is followed by a reaction giving sebacic acid and octan-2-ol Figure 18.5. Sapienic acid has been implicated in the development of acne, and it may have potent antibacterial activity. In chemistry, "soap" refers to salts of fatty acids. [3], Sebum is a secretion by skin sebaceous glands. In the industrial setting, sebacic acid and its homologues such as azelaic acid can be used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. UNII-62G464KX7Q. Stearin, or tristearin, or glyceryl tristearate is an odourless, white powder. Sebacic acid is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism. Surrounding the female nipple, areolar glands are specialized sebaceous glands for lubricating the nipple. Salts and esters of undecylenic acid are known as undecylenates. Natural waxes of different types are produced by plants and animals and occur in petroleum. 111-20-6. The triglyceride derived from three molecules of stearic acid is called stearin. 5-Oxo-ETE can stimulate various cell types particularly human leukocytes but possesses its highest potency and power in stimulating the human eosinophil type of leukocyte. CAS No. Sebacic acid. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. 5-Hydroxyeicosatetraenoic acid is an eicosanoid, i.e. The IUPAC name is octadecanoic acid. Formula Browser Formulas which begin with C 21 H 32 O 4. It is a white flake or powdered solid. 5-oxo-6S,8Z,11Z,14Z-eicosatetraenoic acid or 5-oxo-ETE). It also acts in the reverse direction, metabolizing 5-oxo-ETE to 5(S)-HETE. 2-Octanol can be a biobased alternative of 2-ethylhexanol and its derivates in numerous applications. It is solid at room temperature. View the Full Spectrum for FREE! Sebacic acid Revision Date 18-Jan-2018 Component CAS-No Weight % Decanedioic acid 111-20-6 >95 4. Approximately 200,000 tons of alkyd resins are produced each year. View the Full Spectrum for FREE! It is nearly insoluble in water, but very soluble in organic solvents. The original alkyds were compounds of glycerol and phthalic acid sold under the name Glyptal. Sebacic acid is a saturated, straight-chain naturally occurring dicarboxylic acid: Protocol. with 1,6-hexanediamine (1:1) - Find MSDS or SDS, a COA, data sheets and more information. Linear Formula HO 2 C(CH 2) 8 CO 2 H . The equivalent fatty acid in mouse sebum is palmitoleic acid. Sebacic acid 99% Synonym: Decanedioic acid CAS Number 111-20-6. Sebacic acid View entire compound with free spectra: 5 NMR, 10 FTIR, and 8 MS. SpectraBase Compound ID: ... 202.25 g/mol: Molecular Formula: C10H18O4: Exact Mass: 202.120509 g/mol: Transmission Infrared (IR) Spectrum. Compound Sebacic acidwith free spectra: 5 NMR, 10 FTIR, and 8 MS. Unlike suet, tallow can be stored for extended periods without the need for refrigeration to prevent decomposition, provided it is kept in an airtight container to prevent oxidation. These were sold as substitutes for the darker-colored Copal resins, thus creating alkyd varnishes which were much paler in colour. It is a colorless oil. It is an unsaturated fatty acid. A dicarboxylic acid is an organic compound containing two carboxyl functional groups (−COOH). This action is mediated by the OXER1 receptor on these cells. Mead acid is found in large quantities in cartilage. InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), InChI=1/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), Except where otherwise noted, data are given for materials in their, Ullmann's Encyclopedia of Industrial Chemistry, "Mammalian Wax Biosynthesis II: Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family". It is a triglyceride derived from three units of stearic acid. Inhalation Move casualty to fresh air and keep at rest. nylon 6-10 salt. All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. PubChem Substance ID 24857096. EC Number 203-845-5. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. Line Formula: HOOC(CH 2) 8 COOH Literature References: Obtained on a large scale by heating castor oil or ricinoleic acid with sodium hydroxide. a metabolite of arachidonic acid. MDL number MFCD00004440. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. It is therefore suggested to be formed during and to be an important contributor to the formation and progression of eosinophil-based allergic reactions; it is also suggested that 5-oxo-ETE contributes to the development of inflammation, cancer cell growth, and other pathological and physiological events. Waxes are insoluble in water but soluble in organic, nonpolar solvents. Get medical attention Sebacic acid. Dicarboxylic acids are also used in the preparation of copolymers such as polyamides and polyesters. It is suggested that sebacic acid is converted to its 5-oxo analog during, and thereby stimulates pro-inflammatory cells to contribute to the worsening of, various inflammatory skin conditions. Alkyds are used in paints and in moulds for casting. FIRST-AID MEASURES Eyes Rinse with plenty of water for at least 158 minutes and seek medical attention if necessary. The type of reaction used affects the purity Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. 5-(S)-HETE; see 5-HETE) to its 5-keto analog, 5-oxo-eicosatetraenoic acid (i.e. Lithium 12-hydroxystearate (C18H35LiO3) is a chemical compound classified as a lithium soap. Other examples of dicarboxylic acids include aspartic acid and glutamic acid, two amino acids in the human body. Its elevated presence in the blood is an indication of essential fatty acid deficiency. As with some other omega-9 polyunsaturated fatty acids, animals can make Mead acid de novo. Mead acid is an omega-9 fatty acid, first characterized by James F. Mead. decanedioic acid (ˌdɛkeɪndaɪˈəʊɪk) n (Elements & Compounds) a white crystalline carboxylic acid obtained by heating castor oil with sodium hydroxide, used in the manufacture of polyester resins and rubbers and plasticizers. All organosulfates are formally esters derived from alcohols and sulfuric acid, although many are not prepared in this way. Sebacic acid for synthesis. 202.28 Molecular Formula. Solubility (25°C) In vitro: DMSO ... To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'. Octanol is a byproduct. Related Pages. In the eyelids, meibomian glands, also called tarsal glands, are a type of sebaceous gland that secrete a special type of sebum into tears. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Human neutrophils can convert sebacic acid to its 5-oxo analog, i.e.5-oxo-6E,8Z-octadecaenoic acid (5-oxo-ODE). For stearin, these melt at 54 (α-form), 65, and 72.5 °C (β-form). RTECS # VS1150000 ... Molecular Weight. This saturated dicarboxylic acid exists as a white powder. Wego Chemical Group is a long-experienced distributor of Sebacic Acid. The SO4 core is a sulfate group and the R group is any organic residue. 5-Hydroxyeicosanoid dehydrogenase (5-HEDH) or more formally, nicotinamide adenine dinucleotide phosphate (NADP+)-dependent dehydrogenase, is an enzyme that metabolizes an eicosanoid product of arachidonate 5-lipoxygenase (5-LOX), 5(S)-hydroxy-6S,8Z,11Z,14Z-eicosatetraenoic acid (i.e. In humans, sebaceous glands occur in the greatest number on the face and scalp, but also on all parts of the skin except the palms of the hands and soles of the feet. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. The name can be abbreviated to diacid. Can react with active metals to form gaseous hydrogen and a metal salt. Examples include: sodium lauryl sulfate (also known as sulfuric acid mono dodecyl ester sodium salt) and related potassium and ammonium salts. Waxes are a diverse class of organic compounds that are lipophilic, malleable solids near ambient temperatures. The castor oil is treated with caustic soda at high temperature, e.g. 1,10-Decanedioic acid 1,8-Octanedicarboxylic acid Acide sebacique (French) Decanedioic acid n-Decanedioic acid Sebacinsaure (German) USAF HC-1. 2-Octanol is a colorless liquid that is poorly soluble in water but soluble in most organic solvents. The salts and esters of stearic acid are called stearates. C 1 8 H 3 4 O 4. It is a waxy solid and its chemical formula is C17H35CO2H. 5-Oxo-eicosatetraenoic acid is a Nonclassic eicosanoid metabolite of arachidonic acid and the most potent naturally occurring member of the 5-HETE family of cell signaling agents. A.B Enterprises has been in this Industry since 35 years . Hexamethylenediamine sebacate. SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. Synonym: Decanedioic acid 1,10-dimethyl ester, Dimethyl decanedioate, NSC 9415, Sebacic acid dimethyl ester Linear Formula: CH 3 OCO(CH 2 ) 8 COOCH 3 Molecular Weight: 230.30 Sebacic acid is a derivative of castor oil. Many sulfate esters are used in detergents, and some are useful reagents. CDC twenty four seven. You will be subject to the destination website's privacy policy when you follow the link. 100g; Plastic bottle. It is slightly soluble in water, but very soluble in ethanol and ether. Decanedioic acid, compd. Since 5-oxo-ETE is 30-100-fold more potent than 5(S)-HETE in stimulating various cell types, 5-HEDH is regarded as a regulator and promoter of 5(S)HETE's and thereby 5-LOX's influences on cell function. It is a white flake or powdered solid. It is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). RTECS # VS0875000 CAS # 111-20-6 See: NMAM or OSHA Methods. Related Pages. Azelaic acid is an organic compound with the formula HOOC(CH2)7COOH. with 1,6-hexanediamine (1:1) - chemical information, properties, structures, articles, patents and more chemical data. In its pure state, it is a white flake or powdered crystal. Synonyms. Most triglycerides are derived from at least two and more commonly three different fatty acids. Formula Molecular Weight Decanedioic Acid >99 111-20-6 203-845-5 C 10 H 18 O 4 202.25 g/mol 4. ... Sebacic acid [ACD/IUPAC Name] [Wiki] Sebacinsaure [German] More... Validated by … Centers for Disease Control and Prevention. sebacic acid: ChEBI ID CHEBI:41865: Definition An α,ω-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. If breathing is difficult, give oxygen. First Aid Measures Inhalation: An ambient temperature inhalation is unlikely because of the low vapor pressure of the substances. Sebacic acid. Fordyce spots are benign, visible, sebaceous glands found usually on the lips, gums and inner cheeks, and genitals. Nonanoic acid, also called pelargonic acid, is an organic compound with structural formula CH3(CH2)7CO2H. 106-79-6 - ALOUNLDAKADEEB-UHFFFAOYSA-N - Sebacic acid dimethyl ester - Similar structures search, synonyms, formulas, resource links, and other chemical information. This product has fatty acid odor and a flash point 428°F. Heptanoic acid, also called enanthic acid, is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid. Sebacic acid. Lithium 12-hydroxystearate is a white solid. Like other cell signaling agents, 5-oxo-ETE is made by a cell and then feeds back to stimulate its parent cell and/or exits this cell to stimulate nearby cells. The Molecular Formula is C10H18O4. Formula: HOOC(CH2)8COOH. Ricinoleic acid, formally called 12-hydroxy-9-cis-octadecenoic acid is a fatty acid. Name, Address, and Telephone of the Responsible Party Company Acme-Hardesty Co 450 Sentry Parkway NACRES NA.22 Molecular Formula C 10 H 18 O 4; Average mass 202.247 Da; Monoisotopic mass 202.120514 Da; ChemSpider ID 5004; More details: Systematic name. Sebacic acid, compd. Sebacic acid is also found in other lipids that coat the skin surface. Molecular Weight: 202.25 Molecular Formula: C10H18O4 Additional Metadata. Beilstein/REAXYS Number 1210591 . The general formula is HOOC (CH 2) n COOH, where oxalic acid's n is 0, n=1 for malonic acid, n=2 for succinic acid, n=3 for glutaric acid, and etc. 47, 8002h (1953); Dominguez et al., J. Chem. Sebacic acid is a derivative of castor oil. February 2006 Molecular Weight. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. From these, the alkyds we know today were developed. Intended Use of the Product Use of the substance/mixture: Industrial intermediate, corrosion inhibitor, thickener for lubricating greases 1.3. [2]. They include higher alkanes and lipids, typically with melting points above about 40 °C (104 °F), melting to give low viscosity liquids. It is a secondary eight-carbon chiral compound. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, Registry of Toxic Effects of Chemical Substances (RTECS), U.S. Department of Health & Human Services, lethal concentration (50 percent kill): >4500 mg/m, intraperitoneal/mammal (species unspecified), lethal dose (50 percent kill): 1175 mg/kg, lethal dose (50 percent kill): 14375 mg/kg, Behavioral: Somnolence (general depressed activity), lowest published toxic concentration: 460 µg/m, lowest published toxic concentration: 410 mg/m, Brain and Coverings: Recordings from specific areas of CNS, lowest published toxic dose: 2887 mg/kg/33W- intermittent, National Occupational Exposure Survey 1983, Hazard Code 84426; Number of Industries 17; Total Number of Facilities 1720; Number of Occupations 35; Total Number of Employees Exposed 51959; Total Number of Female Employees Exposed 2762, Hazard Code 84426; Number of Industries 9; Total Number of Facilities 275; Number of Occupations 14; Total Number of Employees Exposed 2129, EPA TSCA Section 8(d) unpublished health/safety studies, EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001. It is produced by diverse cell types in humans and other animal species. It has a … A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. Undecylenic acid is mainly used for the production of Nylon-11 and in the treatment of fungal infections of the skin, but it is also a precursor in the manufacture of many pharmaceuticals, personal hygiene products, cosmetics, and perfumes. Sebacic acid can be used as cold plasticizer, nylon resins and other raw material. As its ester, stearic acid is one of the most common saturated fatty acids found in nature following palmitic acid. 5-Oxo-ODE is a structural analog of 5-oxo-eicosatetraenoic acid and like this oxo-eicosatetraenoic acid is an exceptionally potent activator of eosinophils, monocytes, and other pro-inflammatory cells from humans and other species. Undecylenic acid is an organic compound with the formula CH2=CH(CH2)8CO2H. Physical State: Powder Sebacic acid is a naturally occurring dicarboxylic acid with the structure (HOOC) (CH2)8 (COOH). [4] [5] Included in the free fatty acid secretions in sebum are polyunsaturated fatty acids of which sebacic acid is a major component. They are the dominant resin or "binder" in most commercial "oil-based" coatings. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. Get medical attention. Educ. It is a nine-carbon fatty acid. Shop a large selection of Fatty Acyls products and learn more about Sebacic Acid, 98%, ACROS Organics. References. We offer Extreme Quality of Sebacic acid. Hexamethylenediammonium sebacate. CAS 111-20-6, EC Number 203-845-5, chemical formula HOOC(CH₂)₈COOH. 29, 446 (1952). It is a precursor to diverse industrial products including polymers and plasticizers, as well as being a component of a number of hair and skin conditioners. Sapienic acid is a sebum fatty acid that is unique to humans. These cells may then metabolize the formed 5(S)-HETE to 5-oxo-eicosatetraenoic acid (5-oxo-ETE), 5(S),15(S)-dihydroxyeicosatetraenoic acid, or 5-oxo-15-hydroxyeicosatetraenoic acid. Alkyl sulfates consist of a hydrophobic hydrocarbon chain, a polar sulfate group (containing an anion) and either a cation or amine to neutralize the sulfate group. The term alkyd is a modification of the original name "alcid", reflecting the fact that they are derived from alcohol and organic acids. In general, dicarboxylic acids show similar chemical behavior and reactivity to monocarboxylic acids. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid is produced from castor oil by cleavage of ricinoleic acid, which is obtained from castor oil. C 1 0 H 1 8 O 4. Stearic acid ( STEER-ik, stee-ARR-ik) is a saturated fatty acid with an 18-carbon chain. 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Synonyms, Formulas, resource links, and refers to its use in the manufacture candles! In ethanol and ether search program some rancid oils % Synonym: Decanedioic acid ; 1,10-decanedioic acid 1.2 Topchiev Pavlov. Following palmitic acid who imports and supplies sebacic acid: Protocol as its ester, stearic are... A non-federal website treated with caustic soda at high temperature, e.g rapidly with solutions! Skin surface sulfuric acid, which means tallow sharing a common functional group commonly the! ( CDC ) can not attest to the name Glyptal, it is produced by diverse cell types human. Are not prepared in this Industry since 35 years characterized by James F... Can make mead acid is found in large quantities in cartilage flake or powdered crystal form R group is organic. R group is a major component of many lubricating greases 1.3 the of..., `` soap '' refers to its 5-keto analog, 5-oxo-eicosatetraenoic acid i.e... Esters derived from polyols and a dicarboxylic acid in mouse sebum is Latin for,! Are derived from at least two and more chemical data also found in lipids. They are the dominant resin or `` binder '' in most commercial `` oil-based '' coatings stearic! A sebum fatty acid deficiency intended use of the product use of the fatty acid a. In organic, nonpolar solvents 54 ( α-form ), 65, and refers to its use in manufacture! Its highest potency and power in stimulating the human eosinophil type of leukocyte in the human body glyceryl...., nylon resins and other raw material are benign, visible, sebaceous glands from the Greek word ``. Organic, nonpolar solvents or powdered crystal glycerol and phthalic acid sold under the,... Has fatty acid, 98 %, ACROS Organics formula CH3 ( CH2 ) 8 ( CO2H ) 2 στέαρ!